Lab Equipment
700 MHz NMR Spectrometer
Agilent DirectDrive2
Equipment description:
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- 16.4 T magnetOxford
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- “Direct Drive 2” console
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- four independent RF channels (1H 100 W, BB 400 W, 2 x BB 1000 W), all channels enable for shaped pulses
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- 40 shim coil
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- 2H lock
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- “high band” lock 2H – 1H
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- variable temperature unit
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- XYZ PFG amplifier
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- air termostat FTS (-40 – + 150 ºC)
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- probes (all probes enable variable temperature operation):
- 5 mm 1H/13C/31P-15N/2H, z-PFG (60G/cm), 1H detection
- 5 mm 1H/13C/15N/2H, xyz-PFG (3x60G/cm), 1H detection- biological samplesliquid samples
- 5 mm 1H/31P-15N/2H, z-PFG (60G/cm), BB or 1H detection
- probes (all probes enable variable temperature operation):
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- powder samples:
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- 1H/X/Y, MAS 25 kHz, rotor 3.2 mm,
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- powder samples:
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- heterogenic samples:
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- 4 mm 1H/31P-15N/2H, z-PFG (100 G/cm), 1H detection, MAS
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- heterogenic samples:
Applications:
- new experimental techniques for small organic molecules and macromolecules of biological interest,Methodology of NMR:
- measurements of earlier inaccessible parameters, improvement of precision and accuracy,
- new methods for acquisition multidimensional spectra, with better resolution in shorter time .
- Structural studies of biomolecules
- Application of modern NMR techniques for chiral recognition.
- Studies of host-guest complexes, for example with cyclodextrines.
- Application of residual dipolar couplings and quadrupolar interactions in weakly oriented media in structural studies of organic molecules.
- Investigations of origin of natural compounds using 2H NMR.
- structural studies.
- determination of chemical shift tensor,
- identification of polymorphs,Studies of powder samples in the high magnetic field:
Magritek Spinsolve 43MHz Carbon
- Benchtop NMR Spectrometer
- Double Channel: 1H-13C (43 MHz)
- Standard 5 mm sample tubes
- 50 % Linewidth < 1.0 Hz
Stable over room temperature ± 2° C - External lock system (no requirement for deuterated
solvent) - Spinsolve Expert software
- Reaction monitoring flow-mode system