Lab Equipment

    Lab Equipment

Magritek Spinsolve 43MHz Carbon

  • Benchtop NMR Spectrometer
  • Double Channel: 1H-13C (43 MHz)
  • Standard 5 mm sample tubes
  • 50 % Linewidth < 1.0 Hz
    Stable over room temperature ± 2° C
  • External lock system (no requirement for deuterated
    solvent)
  • Spinsolve Expert software
  • Reaction monitoring flow-mode system

700 MHz NMR Spectrometer     – quenched, not available

Agilent DirectDrive2

 Equipment description:

    • 16.4 T magnetOxford
    • “Direct Drive 2” console
    • four independent RF channels (1H 100 W, BB 400 W, 2 x BB 1000 W), all channels enable for shaped pulses
    • 40 shim coil
    • 2H lock
    • “high band” lock 2H – 1H
    • variable temperature unit
    • XYZ PFG amplifier
    • air termostat FTS (-40 – + 150 ºC)
    • probes (all probes enable variable temperature operation):
      • 5 mm 1H/13C/31P-15N/2H, z-PFG (60G/cm), 1H detection
      • 5 mm 1H/13C/15N/2H, xyz-PFG (3x60G/cm), 1H detection- biological samplesliquid samples
      • 5 mm 1H/31P-15N/2H, z-PFG (60G/cm), BB or 1H detection
    • powder samples:
        • 1H/X/Y, MAS 25 kHz, rotor 3.2 mm,

       

    • heterogenic samples:
        • 4 mm 1H/31P-15N/2H, z-PFG (100 G/cm), 1H detection, MAS

       

 

Applications:

 

  • new experimental techniques for small organic molecules and macromolecules of biological interest,Methodology of NMR:
  • measurements of earlier inaccessible parameters, improvement of precision and accuracy,
  • new methods for acquisition multidimensional spectra, with better resolution in shorter time .
  • Structural studies of biomolecules
  • Application of modern NMR techniques for chiral recognition.
  • Studies of host-guest complexes, for example with cyclodextrines.
  • Application of residual dipolar couplings and quadrupolar interactions in weakly oriented media in structural studies of organic molecules.
  • Investigations of origin of natural compounds using 2H NMR.
  • structural studies.
  • determination of chemical shift tensor,
  • identification of polymorphs,Studies of powder samples in the high magnetic field: