Lab equipment

700 MHz NMR Spectrometer

Varian NMR Systems

 Equipment description:

  • 16.4 T magnetOxford
  • "Direct Drive" console
  • four independent RF channels (1H 100 W, BB 400 W, 2 x BB 1000 W), all channels enable for shaped pulses
  • 40 shim coils
  • 2H lock
  • "high band" lock 2H - 1H
  • variable temperature unit
  • XYZ PFG amplifier
  • air termostat FTS (-40 - + 150 ºC)
  • probes (all probes enable variable temperature operation):
  • liquid samples:
    • 5 mm 1H/13C/15N/2H, xyz-PFG (3x60G/cm), 1H detection- biological samples
    • 5 mm 1H/13C/31P-15N/2H, z-PFG (60G/cm), 1H detection
    • 5 mm 1H/31P-15N/2H, z-PFG (60G/cm), BB or 1H detection
  • powder samples:
    • 1H/X/Y, MAS 25 kHz, rotor 3.2 mm,
  • heterogenic samples:
    • 4 mm 1H/31P-15N/2H, z-PFG (100 G/cm), 1H detection, MAS

Applications:

  • Methodology of NMR:
    • new experimental techniques for small organic molecules and macromolecules of biological interest,
    • measurements of earlier inaccessible parameters, improvement of precision and accuracy, 
    • new methods for acquisition multidimensional spectra, with better resolution in shorter time .
  • Structural studies of biomolecules
  • Application of modern NMR techniques for chiral recognition.
  • Studies of host-guest complexes, for example with cyclodextrines.
  • Application of residual dipolar couplings and quadrupolar interactions in weakly oriented media in structural studies of organic molecules.
  • Investigations of origin of natural compounds using 2H NMR.
  • Studies of powder samples in the high magnetic field:
    • identification of polymorphs,
    • determination of chemical shift tensor,
    • structural studies.