Krzysztof Kazimierczuk

Krzysztof Kazimierczuk

 Contact:

k.kazimierczuk(at)cent.uw.edu.pl

room 00.186 (ground floor)
Banacha 2C, 02-097 Warsaw
tel. +48 22 5544669

Degrees: MSc (Chemistry and Biophysics), PhD (chemistry), DSc (Habilitation, Chemistry)

Titles: Assistant Professor at University of Warsaw, PhD, Dsc

 

Affiliation: Centre of New Technologies, University of Warsaw, Poland

 

 

Education

 

2005 – MSc. Degree in Chemistry at the University of Warsaw. Supervisor: prof. Wiktor Koźmiński.

2007 – MSc. Degree in Biophysics at the University of Warsaw. Supervisors: prof. Ryszard Stolarski and prof. Wiktor Koźmiński.

10.06.2009 – PhD in chemistry (Faculty of Chemistry, University of Warsaw)

08.02.2017 - Habilitation degree in chemistry (Faculty of Chemistry, University of Warsaw)

 

Employment

 

From 1.11.2009 – Employed at the University of Warsaw.

2010 – 2011 – Postdoc at Swedish NMR Center, University of Gothenburg, Sweden. Title of the project: “NMR toolbox for studying intrinsically disordered proteins“.

1.05.2011-15.04.2012 – Postdoc in TEAM programme project ”Towards new applications of NMR spectroscopy in chemical and biomolecular structural studies“ at the University of Warsaw

2012 - current – Head of Laboratory of NMR, Centre of New Technologies, University of Warsaw

 

Honors and Awards

 

2007 – Antoni Grabowski Award for PhD student in Chemistry

 

2008 – Stipend of the Foundation for Polish Science (START programme). Prolongation for 2009.

 

2009 – PhD Thesis ”Methods of fast acquisition of NMR spectra for structural studies” honoured by Faculty Council of the Faculty of Chemistry, University of Warsaw.

 

2010 – PhD Thesis “Methods of fast acquisition of NMR spectra for structural studies” awarded by Prime Minister of Poland Award for PhD Thesis.

 

2014 - Wojciech Świętosławski award of the 2nd grade by the Polish Chemical Society

 

2015 - Wiley Award for the best lecture in NMR spectroscopy: “Dynamic non-uniform sampling”

 

Current scientific interests

Methods of multidimensional NMR. Processing of non-stationary signals. Compressed sensing in spectroscopy and chemistry.

 

 

Paper reviewing

Reviewer in: ChemPhysChem, Journal of Magnetic Resonance, Journal of Biomolecular NMR, Magnetic Resonance in Chemistry, Concepts in Magnetic Resonance, RSC Advances, Springer-PLUS and grants of National Science Centre, Swiss National Science Foundation and French National Research Agency.

 

Overview of teaching activity

 

Introductory seminars in molecular spectroscopy

Laboratory courses in molecular spectroscopy, physics and physical chemistry

Popular science: lecture and laboratory practice for high-school students etc.

International courses in biomolecular NMR spectroscopy organized in Swedish NMR Centre, Masaryk University (Brno), Spronk Consultancy (Vilinius), Polish Academy of Sciences (Łodź) and at the University of Warsaw

 

Research projects

 

1. KOLUMB stipend (Foundation for Polish Science): "NMR toolbox for studying intrinsically disordered proteins“ (2011)

2. IUVENTUS PLUS grant (Ministry of Science and Higher Education), project: ”Reconstruction of NMR spectra from incomplete data with compressed sensing algorithms“ (2012-2014)

3. SONATA-BIS 2 grant (National Centre of Science): ”Sparse and approximately-sparse representations in problems of NMR spectroscopy“ (2013-2018)

4. HARMONIA 2 grant (National Centre of Science): ”Regularization algorithms for the processing of NMR spectra of metabolite mixtures“ (2013-2014)

5. ”Inkubator Innowacyjności“ (Ministry of Science and Higher Education): ”Statusino - mobile application for monitoring status of NMR spectrometers“

6. OPUS 9 grant (National Centre of Science): ”Time-resolved N-dimensional spectroscopy for monitoring of physical and chemical processes “ (2016-2018)

7. HARMONIA 9 grant (National Centre of Science): ”Radon transform in NMR spectroscopy of proteins“ (2018-2021)

8. FIRST TEAM grant (Foundation for Polish Science): ”Methods of non-stationary signal analysis for more sensitive NMR spectroscopy“ (2018-2021)

 

Selected Publications

 

1. Kazimierczuk, Krzysztof, Wiktor Koźmiński, and Igor Zhukov. Two-dimensional Fourier transform of arbitrarily sampled NMR data sets. Journal of Magnetic Resonance, 179(2):323–328, 2006.

2. Kazimierczuk, Krzysztof, Anna Zawadzka, Wiktor Koźmiński, and Igor Zhukov. Random sampling of evolution time space and Fourier transform processing. Journal of Biomolecular NMR, 36(3):157–168, 2006.

3. Kazimierczuk, Krzysztof, Anna Zawadzka, Wiktor Koźmiński, and Igor Zhukov. Lineshapes and

artifacts in Multidimensional Fourier Transform of arbitrary sampled NMR data sets. Journal of

Magnetic Resonance, 188(2):344–356, 2007.

4. Kazimierczuk, Krzysztof, Anna Zawadzka, Wiktor Koźmiński, and Igor Zhukov. Determination

of spin-spin couplings from ultrahigh resolution 3D NMR spectra obtained by optimized random

sampling and multidimensional fourier transformation. Journal of the American Chemical Society,

130(16):5404–5405, 2008.

5. Kazimierczuk, Krzysztof, Anna Zawadzka, and Wiktor Koźmiński. Optimization of random time

domain sampling in multidimensional NMR. Journal of Magnetic Resonance, 192(1):123–130, 2008.

6. Kazimierczuk, Krzysztof, Anna Zawadzka, and Wiktor Koźmiński. Narrow peaks and high dimensionalities: Exploiting the advantages of random sampling. Journal of Magnetic Resonance, 197(2):219–228, 2009.

7. Anna Zawadzka-Kazimierczuk, Kazimierczuk, Krzysztof, and Wiktor Koźmiński. A set of 4D NMRexperiments of enhanced resolution for easy resonance assignment in proteins. Journal of Magnetic Resonance, 202(1):109–116, 2010.

8. Kazimierczuk, Krzysztof, Anna Zawadzka-Kazimierczuk, and Wiktor Koźmiński. Non-uniform frequency domain for optimal exploitation of non-uniform sampling. Journal of Magnetic Resonance, 205(2):286–292, 2010.

9. Kazimierczuk, Krzysztof, Jan Stanek, Anna Zawadzka-Kazimierczuk, and Wiktor Koźmiński. Random sampling in multidimensional NMR spectroscopy. Progress in Nuclear Magnetic Resonance Spectroscopy, 57(4):420–434, 2010.

10. Motáčková, Veronika and Nováček, Jiri and Zawadzka-Kazimierczuk, Anna and Kazimierczuk,

Krzysztof and Žídek, Lukas and Šanderová, Hanna and Krásný, Libor and Koźmiński, Wiktor and

Sklenář, Vladimir. Strategy for complete NMR assignment of disordered proteins with highly repeti

tive sequences based on resolution-enhanced 5D experiments. Journal of Biomolecular NMR, 48(3):169–177, 2010.

11. Kazimierczuk, Krzysztof and Vladislav Yu. Orekhov. Accelerated NMR spectroscopy by using compressed sensing. Angewandte Chemie - International Edition, 50(24):5556–5559, 2011.

12. Kazimierczuk, Krzysztof and Vladislav Yu. Orekhov. A comparison of convex and non-convex compressed sensing applied to multidimensional NMR. J. Magn. Reson., 223:1–10, 2012.

13. Mateusz Urbańczyk, Diana Bernin, Wiktor Koźmiński, and K. Kazimierczuk. Iterative thresholding algorithm for multiexponential decay applied to pgse nmr data. Analytical Chemistry, 85(3):1828–1833, 2013.

14. Kazimierczuk, Krzysztof, Olivier Lafon, and Philippe Lesot. Criteria for sensitivity enhancement by compressed sensing: Practical application to anisotropic nad 2d-nmr spectroscopy. Analyst, 139(11):2702–2713, 2014.

15. Mateusz Urbańczyk, Wiktor Koźmiński, and Kazimierczuk, Krzysztof. Accelerating diffusion-

ordered nmr spectroscopy by joint sparse sampling of diffusion and time dimensions. Angewandte

Chemie - International Edition, 53(25):6464–6467, 2014.

16. Wolfgang Bermel, Dass, Rupashree, Klaus-Peter Neidig, and Kazimierczuk, Krzysztof. Two-

dimensional nmr spectroscopy with temperature-sweep. ChemPhysChem, 15(11):2217–2220, 2014.

17. Maxim Mayzel, Kazimierczuk, Krzysztof, and Vladislav Yu. Orekhov. The causality principle in the reconstruction of sparse NMR spectra. Chemical Communications, 50(64):8947–8950, 2014.

18. Dass, Rupashree, Wiktor Koźmiński, and Kazimierczuk, Krzysztof. Analysis of Complex Reacting Mixtures by Time-Resolved 2D NMR. Analytical Chemistry, 87(2):1337–1343, 2015.

19. Kazimierczuk, Krzysztof and Vladislav Orekhov. Non-uniform sampling: post-Fourier era of NMR data collection and processing. Magnetic resonance in chemistry : MRC, 53(11):921–6, dec 2015.

20. Ikenna Edward Ndukwe, Shchukina, Alexandra, Kazimierczuk, Krzysztof, and Craig Philip Butts. Rapid and safe ASAP acquisition with EXACT NMR. Chem. Commun., 2(2):303, 2016.

21. Shchukina, Alexandra, Paweł Kasprzak, Dass, Rupashree, Michał Nowakowski, and Kazimierczuk, Krzysztof. Pitfalls in compressed sensing reconstruction and how to avoid them. Journal of Biomolecular NMR, pages 1–20, 2016.

22. Dass, Rupashree, Paweł Kasprzak, and Kazimierczuk, Krzysztof. Quick, sensitive serial NMR experiments with Radon transform. Journal of Magnetic Resonance, 282:114–118, 2017. Pkt. MNiSW (2016):30