Krzysztof Kazimierczuk

Krzysztof Kazimierczuk

 Contact:

k.kazimierczuk(at)cent.uw.edu.pl

room 00.186 (ground floor)
Banacha 2C, 02-097 Warsaw
tel. +48 22 5544669

Education

  • 1999-2007 Student of Interdisciplinary School for Mathematics and Science at University of Warsaw.
  • 2005 – MSc. Degree in Chemistry at the University of Warsaw. Supervisor: prof. Wiktor Koźmiński.
  • 2007 – MSc. Degree in Biophysics at the University of Warsaw. Supervisors: prof. Ryszard Stolarski and prof. Wiktor Koźmiński.
  • 2005 – 2009  PhD Student at the Faculty of Chemistry, University of Warsaw in prof. Wiktor Koźmiński’s group.
  • 10.06.2009 – PhD in chemistry, thesis entitled: “Methods of fast acquisition of NMR spectra for structural studies”.

Employment

  • 2002-2009 Employed in the Foundation for Diagnostics and Therapy as chemist (organic synthesis and purification).
  • From 1.11.2009 – Employed at the University of Warsaw.
  • 1.02.2010 – 15.04.2011 – Postdoc at Swedish NMR Center, University of Gothenburg, Sweden. Title of the project: “NMR toolbox for studying intrinsically disordered proteins“.
  • 1.05.2011-15.04.2012 – Postdoc in TEAM programme project ”Towards new applications of NMR spectroscopy in chemical and biomolecular structural studies“ at the University of Warsaw
  • 2012-current – Head of Laboratory of NMR, Centre of New Technologies, University of Warsaw

Honors and Awards

  • 2005 – First Award in Poster Session presenting MSc. results
  • 2007 – Antoni Grabowski Award for PhD student in Chemistry
  • 2008 – Stipend of the Foundation for Polish Science (START programme). Prolongation for 2009.
  • 2009 – Nominated as a ”Young Researcher“ for Nobel Laureates Meeting in Lindau
  • 2009 – PhD Thesis ”Methods of fast acquisition of NMR spectra for structural studies” honoured by Faculty Council of the Faculty of Chemistry, University of Warsaw.
  • 2010 – Postdoc stipend funded by the Foundation for Polish Science (KOLUMB programme).
  • 2010 – PhD Thesis “Methods of fast acquisition of NMR spectra for structural studies” awarded by Prime Minister of Poland Award for PhD Thesis.
  • 2014 - Wojciech Świętosławski award of the 2nd grade by the Polish Chemical Society

Current scientific interests

Methods of multidimensional NMR. Compressed sensing in spectroscopy and chemistry.

Publications

  1. K. Kazimierczuk and W. Koźmiński. Efficient compensation of low-frequency magnetic field disturbances in NMR with fluxgate sensors. Journal of Magnetic Resonance, 174(2):287-291, 2005.
  2. K. Kazimierczuk, W. Koźmiński, and I. Zhukov. Two-dimensional Fourier transform of arbitrarily sampled NMR data sets. Journal of Magnetic Resonance, 179(2):323-328, 2006.
  3. K. Kazimierczuk and W. Koźmiński. On the influence of low-frequency magnetic field disturbances on basic high resolution NMR experiments. Polish Journal of Chemistry, 80(7):1119-1124, 2006.
  4. K. Kazimierczuk, A. Zawadzka, W. Koźmiński, and I. Zhukov. Random sampling of evolution time space and Fourier transform processing. Journal of Biomolecular NMR, 36(3):157-168, 2006.
  5. K. Kazimierczuk, A. Zawadzka, W. Koźmiński, and I. Zhukov. Lineshapes and artifacts in Multidimensional Fourier Transform of arbitrary sampled NMR data sets. Journal of Magnetic Resonance, 188(2):344-356, 2007.
  6. K. Kazimierczuk, M. Misiak, A. Zawadzka, and W. Koźmiński. Progress in structural studies of proteins by NMR spectroscopy. Polimery/Polymers, 52(10):736-744, 2007.
  7. K. Kazimierczuk, A. Zawadzka, W. Koźmiński, and I. Zhukov. Determination of spin-spin couplings from ultrahigh resolution 3D NMR spectra obtained by optimized random sampling and multidimensional fourier transformation. Journal of the American Chemical Society, 130(16):5404-5405, 2008.
  8. K. Kazimierczuk, A. Zawadzka, and W. Koźmiński. Optimization of random time domain sampling in multidimensional NMR. Journal of Magnetic Resonance, 192(1):123-130, 2008.
  9. K. Kazimierczuk, A. Zawadzka, and W. Koźmiński. Narrow peaks and high dimensionalities: Exploiting the advantages of random sampling. Journal of Magnetic Resonance, 197(2):219-228, 2009.
  10. A. Zawadzka-Kazimierczuk, K. Kazimierczuk, and W. Koźmiński. A set of 4D NMR experiments of enhanced resolution for easy resonance assignment in proteins. Journal of Magnetic Resonance, 202(1):109-116, 2010.
  11. K. Kazimierczuk, A. Zawadzka-Kazimierczuk, and W. Koźmiński. Non-uniform frequency domain for optimal exploitation of non-uniform sampling. Journal of Magnetic Resonance, 205(2):286-292, 2010.
  12. K. Kazimierczuk, J. Stanek, A. Zawadzka-Kazimierczuk, and W. Koźmiński. Random sampling in multidimensional NMR spectroscopy. Progress in Nuclear Magnetic Resonance Spectroscopy, 57(4):420-434, 2010.
  13. V. Motackova J. Novacek, A. Zawadzka-Kazimierczuk, K. Kazimierczuk, L. Zidek, H. Sanderova, L. Krasny W. Koźmiński, and V. Sklenar. Strategy for complete NMR assignment of disordered proteins with highly repetitive sequences based on resolution-enhanced 5D experiments. Journal of Biomolecular NMR, 48(3):169-177, 2010. 
  14. K. Kazimierczuk and V.Yu. Orekhov. Accelerated NMR spectroscopy by using compressed sensing. Angewandte Chemie - International Edition, 50(24):5556-5559, 2011.
  15. D. Lozhko, J. Stanek, K. Kazimierczuk, A. Zawadzka-Kazimierczuk, W. Kozminski, I. Zhukov, and A. Kornelyuk. H, C, and N chemical shifts assignments for human endothelial monocyte-activating polypeptide EMAP II. Biomolecular NMR Assignments, pages 1-5, 2012.
  16. K. Kazimierczuk, Misiak M., J. Stanek, A. Zawadzka-Kazimierczuk, and Koźmiński W. Generalized fourier transform for non-uniform sampled data. Top Curr Chem, 316:79-124, 2012.
  17. K. Kazimierczuk and V.Yu. Orekhov. A comparison of convex and non-convex compressed sensing applied to multidimensional NMR. J. Magn. Reson., 223:1-10, 2012.
  18. M. Misiak, W. Koźmiński, K. Chmurski, and K. Kazimierczuk. Study of near-symmetric cyclodextrins by compressed sensing 2D NMR. Magnetic Resonance in Chemistry, 51(2):110-115, 2013.
  19. M. Urbańczyk, D. Bernin, W. Koźmiński, and K. Kazimierczuk. Iterative thresholding algorithm for multiexponential decay applied to PGSE NMR data. Analytical Chemistry, 85(3):1828-1833, 2013.
  20. L. Wu, A. Reymer, C. Persson, K. Kazimierczuk, T. Brown, P. Lincoln, B. Norden, and M. Billeter. Initial DNA interactions of the binuclear threading intercalator ,-[-bidppz(bipy)4Ru2]4+: An NMR study with [d(CGCGAATTCGCG)]2. Chemistry - A European Journal, 19(17):5401-5410, 2013.
  21. K. Kazimierczuk, J. Stanek, A. Zawadzka-Kazimierczuk, and W. Koźmiński. High-dimensional NMR spectra for structural studies of biomolecules. ChemPhysChem, 14(13):3015-3025, 2013.
  22. K. Kazimierczuk, O. Lafon, and P. Lesot. Criteria for Sensitivity Enhancement by Compressed Sensing: Practical application to Anisotropic NAD 2D-NMR Spectroscopy. Analyst, DOI:10.1039/C4AN00381K(13), 2014.
  23. M. Urbańczyk, W. Koźmiński, and K. Kazimierczuk. Accelerating diffusion-ordered NMR by joint sparse sampling of diffusion and time dimensions. Angewandte Chemie International Edition, DOI:10.1002/anie.201402049R3, 2014.
  24. W. Bermel, R. Dass, K-P Neidig, and K. Kazimierczuk. Two-dimensional NMR spectroscopy with temperature sweep. ChemPhysChem, DOI: 10.1002/cphc.201402191, 2014.